School of Medicine

Index of publications

• Articles
  • 2012
  • 2011
  • 2010
  • 2007
  • 2006
  • 2005
  • 2004
  • 2003
  • 2002
  • 2000
• Conference proceedings
  • 2012
  • 2011
  • 2010
  • 2007
  • 2005
  • Undated

Publications

• Articles
  • 2012
    • Avidity of influenza-specific memory CD8+ T-cell populations decays over time compromising antiviral immunity.
      Humphreys IR, Clement M, Marsden M, Ladell K, McLaren JE, Smart K, Hindley JP, Bridgeman HM, van den Berg HA, Price DA, Ager A, Wooldridge L, Godkin A, Gallimore AM, Eur J Immunol, Volume 42, 12 (December 2012) pp.3235-3242
    • Rapid early innate control of hepatitis C virus during IFN-α treatment compromises adaptive CD4+ T-cell immunity.
      Pembroke T, Rees I, Gallagher K, Jones E, Mizen P, Navruzov T, Freedman A, Fielding C, Humphreys IR, Wang EC, Gallimore AM, Godkin A, Eur J Immunol, Volume 42, 9 (September 2012) pp.2383-2394
    • The death receptor 3/TL1A pathway is essential for efficient development of antiviral CD4⁺ and CD8⁺ T-cell immunity.
      Twohig JP, Marsden M, Cuff SM, Ferdinand JR, Gallimore AM, Perks WV, Al-Shamkhani A, Humphreys IR, Wang EC, Faseb J, Volume 26, 8 (August 2012) pp.3575-3586
    • Herpesvirus exploitation of host immune inhibitory pathways.
      Stack G, Stacey MA, Humphreys IR, Viruses, Volume 4, 8 (August 2012) pp.1182-1201
  • 2011
    • IL-10 restricts activation-induced death of NK cells during acute murine cytomegalovirus infection.
      Stacey MA, Marsden M, Wang EC, Wilkinson GW, Humphreys IR, J Immunol, Volume 187, 6 (September 2011) pp.2944-2952
  • 2010
    • Biphasic role of 4-1BB in the regulation of mouse cytomegalovirus-specific CD8(+) T cells.
      Humphreys IR, Lee SW, Jones M, Loewendorf A, Gostick E, Price DA, Benedict CA, Ware CF, Croft M, Eur J Immunol, Volume 40, 10 (October 2010) pp.2762-2768
    • IL-10 restricts memory T cell inflation during cytomegalovirus infection.
      Jones M, Ladell K, Wynn KK, Stacey MA, Quigley MF, Gostick E, Price DA, Humphreys IR, J Immunol, Volume 185, 6 (September 2010) pp.3583-3592
  • 2007
    • OX40 costimulation promotes persistence of cytomegalovirus-specific CD8 T Cells: A CD4-dependent mechanism.
      Humphreys IR, Loewendorf A, de Trez C, Schneider K, Benedict CA, Munks MW, Ware CF, Croft M, J Immunol, Volume 179, 4 (August 2007) pp.2195-2202
    • Cytomegalovirus exploits IL-10-mediated immune regulation in the salivary glands.
      Humphreys IR, de Trez C, Kinkade A, Benedict CA, Croft M, Ware CF, J Exp Med, Volume 204, 5 (May 2007) pp.1217-1225
  • 2006
    • A critical role for ICOS co-stimulation in immune containment of pulmonary influenza virus infection.
      Humphreys IR, Edwards L, Snelgrove RJ, Rae AJ, Coyle AJ, Hussell T, Eur J Immunol, Volume 36, 11 (November 2006) pp.2928-2938
    • A role for dendritic cells in the dissemination of mycobacterial infection.
      Humphreys IR, Stewart GR, Turner DJ, Patel J, Karamanou D, Snelgrove RJ, Young DB, Microbes Infect, Volume 8, 5 (April 2006) pp.1339-1346
  • 2005
    • Evolutionarily divergent herpesviruses modulate T cell activation by targeting the herpesvirus entry mediator cosignaling pathway.
      Cheung TC, Humphreys IR, Potter KG, Norris PS, Shumway HM, Tran BR, Patterson G, Jean-Jacques R, Yoon M, Spear PG, Murphy KM, Lurain NS, Benedict CA, Ware CF, Proc Natl Acad Sci U S A, Volume 102, 37 (September 2005) pp.13218-13223
    • TGF-beta prevents eosinophilic lung disease but impairs pathogen clearance.
      Williams AE, Humphreys IR, Cornere M, Edwards L, Rae A, Hussell T, Microbes Infect, Volume 7, 3 (March 2005) pp.365-374
    • The stress-responsive chaperone alpha-crystallin 2 is required for pathogenesis of Mycobacterium tuberculosis.
      Stewart GR, Newton SM, Wilkinson KA, Humphreys IR, Murphy HN, Robertson BD, Wilkinson RJ, Young DB, Mol Microbiol, Volume 55, 4 (February 2005) pp.1127-1137
  • 2004
    • Innate imprinting by the modified heat-labile toxin of Escherichia coli (LTK63) provides generic protection against lung infectious disease
      Williams AE, Edwards L, Humphreys IR, Snelgrove R, Rae A, Rappuoli R, Hussell T, Journal Of Immunology, Volume 173, 12 (December 2004) pp.7435-7443
    • Mucosal immunisation of murine neonates using whole cell and acellular Pertussis vaccines.
      Hale C, Humphreys IR, Hussell T, Bowe F, Clare S, Pickard D, Preston A, Del Giudice G, Dougan G, Vaccine, Volume 22, 27-28 (September 2004) pp.3595-3602
    • Co-stimulation: novel methods for preventing viral-induced lung inflammation.
      Hussell T, Snelgrove R, Humphreys IR, Williams AE, Trends Mol Med, Volume 10, 8 (August 2004) pp.379-386
  • 2003
    • A critical role for OX40 in T cell-mediated immunopathology during lung viral infection.
      Humphreys IR, Walzl G, Edwards L, Rae A, Hill S, Hussell T, J Exp Med, Volume 198, 8 (October 2003) pp.1237-1242
    • OX40 ligation on activated T cells enhances the control of Cryptococcus neoformans and reduces pulmonary eosinophilia.
      Humphreys IR, Edwards L, Walzl G, Rae AJ, Dougan G, Hill S, Hussell T, J Immunol, Volume 170, 12 (June 2003) pp.6125-6132
    • Prior exposure to live Mycobacterium bovis BCG decreases Cryptococcus neoformans-induced lung eosinophilia in a gamma interferon-dependent manner.
      Walzl G, Humphreys IR, Marshall BG, Edwards L, Openshaw PJ, Shaw RJ, Hussell T, Infect Immun, Volume 71, 6 (June 2003) pp.3384-3391
  • 2002
    • Nasal vaccination induces protective immunity without immunopathology
      Hussell T, Humphreys IR, Clinical And Experimental Immunology, Volume 130, 3 (December 2002) pp.359-362
    • Interleukins 5 and 13 characterize immune responses to respiratory sensitizing acid anhydrides.
      Dearman RJ, Filby A, Humphreys IR, Kimber I, J Appl Toxicol, Volume 22, 5 (September 2002) pp.317-325
  • 2000
    • Characterization in mice of the immunological properties of five allergenic acid anhydrides.
      Dearman RJ, Warbrick EV, Humphreys IR, Kimber I, J Appl Toxicol, Volume 20, 3 (May 2000) pp.221-230
• Conference proceedings
  • 2012
    • THE REGULATION OF ARTHRITIC BONE EROSIONS BY IL-10
      Greenhill CJ, Williams AS, Jones GW, Nowell MA, Moideen AN, Rosas M, Taylor PR, Humphreys IR, Jones SA, Rheumatology, Volume 51 (May 2012) pp.48-48
  • 2011
    • The regulation of arthritic bone erosions by IL-10
      Greenhill CJ, Williams AS, Jones GW, Nowell MA, Rosas M, Taylor PR, Humphreys IR, Jones SA, Immunology, Volume 135 (December 2011) pp.158-158
    • Efficient generation of anti-viral CD8(+) T cell immunity is dependent on the death receptor 3/TL1A pathway
      Twohig JP, Marsden M, Cuff SM, Ferdinand JR, Gallimore AM, Perks WV, Al-Shamkhani A, Humphreys IR, Wang ECY, Immunology, Volume 135 (December 2011) pp.56-56
  • 2010
    • Interleukin-10 affords early protection from murine cytomegalovirus infection by inhibiting NK cell apoptosis
      Stacey MA, Marsden M, Wang EC, Wilkinson GW, Humphreys IR, Immunology, Volume 131 (December 2010) pp.39-39
    • Interleukin-10 affords early protection from murine cytomegalovirus infection by inhibiting NK cell apoptosis
      Stacey MA, Marsden M, Wang EC, Wilkinson GW, Humphreys IR, Immunology, Volume 131 (December 2010) pp.29-29
  • 2007
    • IL-10 mediated immune regulation in the salivary gland facilitates cytomegalovirus persistence
      Humphreys IR, de Trez C, Kinkade A, Benedict CA, Croft M, Ware CF, Immunology, Volume 120 (March 2007) pp.25-25
  • 2005
    • OX40 mediates CD8 T cell responses to persistent murine cytomegalovirus (MCMV) infection
      Humphreys IR, Schneider K, Benedict C, Munks M, Hill A, Ware C, Croft M, Faseb Journal, Volume 19, 4 (March 2005) pp.A397-A397
  • Undated
    • The death receptor 3/TL1A pathway regulates acute antiviral CD4+ and CD8+ T cell immunity
      Twohig J, Marsden M, Cuff SM, Ferdinand JR, Gallimore AM, Perks WV, Al-Shamkhani A, Humphreys IR, Wang EC, , Glasgow, Scotland (September 2012) Immunology, Volume 137 (Suppl. 1) p. 144