Medical Microbiology & Infectious Diseases
Academic Lead
Clinical Lead
Principle Investigators:
The research theme of Medical Microbiology and Infectious Diseases brings together world class research with a strong track record on undergraduate and postgraduate teaching. We are constantly looking for innovative ways to develop academic medical microbiology and clinical infection research within Wales.
The close links established with the NHS facilitate translational research and allow clinical evaluation of novel methodologies and diagnostics. Close links with industrial partners are established and there is a broad portfolio of research interest with particular strengths in virology, viral immunology, antimicrobial resistance and diagnosis of fungal infection.
Selected Recent Publications
- Expression of CD200 on AML blasts directly suppresses memory T-cell function.
Coles SJ et al, Leukemia - Increased CD200 expression in acute myeloid leukemia is linked with an increased frequency of FoxP3(+) regulatory T cells.
Coles SJ et al, Leukemia - Human cytomegalovirus UL40 signal peptide regulates cell surface expression of the NK cell ligands HLA-E and gpUL18.
Prod'homme V et al, J Immunol - Expansion of a CD8(+)PD-1(+) replicative senescence phenotype in early stage CLL patients is associated with inverted CD4:CD8 ratios and disease progression.
Nunes C et al, Clin Cancer Res - High-resolution human cytomegalovirus transcriptome.
Gatherer D et al, Proc Natl Acad Sci U S A